Shift

1. Shift is the process in which the existing H ( hemagglutinin) and N ( neuraminidase) are replaced by significantly different H and Ns.

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Notes: These new H or H/N combinations are perceived by human immune systems as new, so most people do not have pre-existing antibody protection to these novel viruses. This is one of the reasons that pandemic viruses can have such a serve impact on the health of populations.

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(Source: Business Continuity Management Institute - BCM Institute)

A Manager’s Guide to Implementing Your Infectious Disease Business Continuity Plan

A Manager’s Guide to ISO 22301 Standard for Business Continuity Management System